Dr Nina Pollak

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Dr Nina Pollak

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CSIRO Future Science Synthetic Biology Fellow

PhD, University of Graz (KFUG) Austria,. MSc, University of Graz (KFUG) Austria,. BSc, University of Graz (KFUG) Austria.

Email
Telephone
+61 7 5456 5009
Office location
I.2.12.A
Dr Nina Pollak

Profile

Dr Nina Pollak completed her PhD in Biochemistry and Molecular Biology at the University of Graz, Austria in 2014. In 2017, Nina has received a CSIRO Synthetic Biology Future Science Fellowship, which she holds jointly at CSIRO and the University of the Sunshine Coast.

Nina’s research uses synthetic biology technology to build a pseudo-organism to target, break down and remove pollution in the water. Her research presents an extremely innovative approach to extending the boundaries of synthetic biology by integrating it with the field of tissue engineering. As a synthetic biologist, Nina believes that this highly interdisciplinary field of science offers new opportunities to protect and remediate the environment. It is her vision to create a smarter, greener and more sustainable world.

Publications

Journal articles
  1. James, A.S., Todd, S., Pollak, N.M., Marsh, G.A., Macdonald, J., 2018, Ebolavirus diagnosis made simple, comparable and faster than molecular detection methods: preparing for the future., Virology Journal, 15(1):75.
  2. Pollak, N.M.#, Hoffman, M.#, Goldberg, I.J., Drosatos, K., 2018, Krüppel-Like Factors: Crippling and Uncrippling Metabolic Pathways., JACC: Basic to Translational Science 3(1): 132-156. #Authors contributed equally.
  3. Drosatos, K.#, Pollak, N.M.#, Pol, C., Ntziachristos, P., Willecke, F., Valenti, M.C., Trent, C.M., Hu, Y., Guo, S., Aifantis, I., Goldberg, I.J., 2016, Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function., Circulation Research 118(2):241-53. #Authors contributed equally.
  4. Jaeger, D., Schoiswohl, G., Hofer, P., Schreiber, R., Schweiger, M., Eichmann, T.O., Pollak, N.M., Poecher, N., Grabner, G.F., Zierler, K.A., Eder, S., Kolb, D., Radner, F.P., Preiss-Landl, K., Lass, A., Zechner, R., Kershaw, E.E., Haemmerle, G., 2015, Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids., Journal of Hepatology 63(2):437-45.
  5. Drosatos, K., Lymperopoulos, A., Kennel, P.J., Pollak, N.M., Schulze, P.C., Goldberg, I.J., 2015, Pathophysiology of Sepsis-Related Cardiac Dysfunction: Driven by Inflammation, Energy Mismanagement, or Both?, Current Heart Failure Reports 12(2):130-40.
  6. Pollak, N.M., Jaeger, D., Kolleritsch, S., Zimmermann, R., Zechner, R., Lass, A., Haemmerle, G., 2015, The interplay of protein kinase A and perilipin 5 regulates cardiac lipolysis., Journal of Biological Chemistry 16;290(3):1295-306.
  7. Brahma, M.K., Adam, R.C., Pollak, N.M., Jaeger, D., Zierler, K.A., Poecher, N., Schreiber, R., Romauch, M., Moustafa, T., Eder, S., Ruelicke, T., Preiss-Landl, K., Lass, A., Zechner, R., Haemmerle, G., 2014, FGF21 is induced upon cardiac stress and alters cardiac lipid homeostasis., Journal of Lipid Research 55(11):2229-41.
  8. Zierler, K.A., Jaeger, D., Pollak, N.M., Eder, S., Rechberger, G.N., Radner, F.P., Woelkart, G., Kolb, D., Schmidt, A., Kumari, M., Preiss-Landl, K., Pieske, B., Mayer, B., Zimmermann, R., Lass, A., Zechner, R., Haemmerle, G., 2013, Functional cardiac lipolysis in mice critically depends on comparative gene identification-58., Journal of Biological Chemistry 288(14):9892-904.
  9. Pollak, N.M., Schweiger, M., Jaeger, D., Kolb, D., Kumari, M., Schreiber, R., Kolleritsch, S., Markolin, P., Grabner, G.F., Heier, C., Zierler, K.A., Ruelicke, T., Zimmermann, R., Lass, A., Zechner, R., Haemmerle, G., 2013, Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier., Journal of Lipid Research 54(4):1092-102.
  10. Haemmerle, G., Moustafa, T., Woelkart, G., Buettner, S., Schmidt, A., van de Weijer, T., Hesselink, M., Jaeger, D., Kienesberger, P.C., Zierler, K., Schreiber, R., Eichmann, T., Kolb, D., Kotzbeck, P., Schweiger, M., Kumari, M., Eder, S., Schoiswohl, G., Wongsiriroj, N., Pollak, N.M., Radner, F.P., Preiss-Landl, K., Kolbe, T., Ruelicke, T., Pieske, B., Trauner, M., Lass, A., Zimmermann, R., Hoefler, G., Cinti, S., Kershaw, E.E., Schrauwen, P., Madeo, F., Mayer, B., Zechner, R., 2011, ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1., Nature Medicine 17(9):1076-85
Conference papers
  1. Pol, C.J., Pollak, N.M., Jurczak, M.J., Karagiannides, I., Ntziachristos, P., Scerbo, D.A., Brown, B.R., Valenti, M.C., Aifantis, I., Shulman, G.I., Goldberg, I.J., Drosatos, K., 2017, Cardiomyocyte-Specific KLF5 Deletion Accelerates Diet-Induced Obesity via Cardiac FGF21., Circulation 136 (Suppl 1):A17746-A17746.
  2. Pol, C.J., Pollak, N.M., Jurczak, M.J., Karagiannides, I., Ntziachristos, P., Scerbo, D.A., Aifantis, I., Shulman, G.I., Goldberg, I.J., Drosatos, K., 2017, Cardiac Myocyte KLF5 Regulates Adiposity via Alteration of Cardiac FGF21., The FASEB Journal 31 (1 Supplement), 624.2-624.2.
  3. Drosatos, K., Pollak, N.M., Willecke, F., Ntziachristos, P., Trent, C.M., Hu, Y., Schulze, C.P., Aifantis, I., Goldberg, I.J., 2014, Klf5 Mediates Glucose-driven Changes of Ccardiac Pparα in Diabetes., Circulation 130 (Suppl 2):A17827-A17827.
  4. Drosatos, K., Pollak, N.M., Jurczak, M.J., Ntziachristos, P., Trent, C.M., Hu, Y., Aifantis, I., Shulman, G.I., Goldberg, I.J., 2014, Klf5 is a Transcriptional Regulator of Cardiac Med13 and Affects High Fat Diet-induced Obesity., Circulation 130 (Suppl 2):A17916-A17916.
  5. Drosatos, K., Pollak, N.M., Ntziachristos, P., Trent, C.M., Hu, Y., Homma, S., Aifantis, I., Goldberg, I.J., 2014, Abstract O-1: Klf5 Regulates Cardiac Pparα and Med13 and affects Cardiac Fatty Acid Metabolism And Obesity., Circulation Research 115 (Suppl 1): AO-1-AO-1.
  6. Zierler, K.A., Jaeger, D., Pollak, N.M., Zechner, R., Haemmerle, G., 2010, P262 Defective TG catabolism and substrate oxidation in mice lacking CGI-58 in oxidative tissues., Atherosclerosis Supplements 11(2):71.

Research grants

Project name Investigator Funding body Year(s) of operation

Tissue engineered multicellular structures for aquatic detoxification.

Advance synthetic biology technology to build a pseudo-organism to target, break down and remove pollution in water.

Dr Nina Pollak

CSIRO/USC $470.790

2017-2020

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